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연구/발표논문

연구/발표논문 자세히 보기

유영춘 교수 (Yoo, Yung Choon)

연구분야

  • 면역조절제의 개발과 면역학적 기전 해석에 관한 연구
  • 면역 adjuvant를 탐색하여 vaccine개발과 종양의 면역학적 치료 및 예방에 응용하고자 하는 연구
  • 종양세포 apoptosis유도 물질을 탐색하고, 그 작용기전을 해석하는 연구
  • 종양치료에 응용 가능한 항암면역치료 후보물질 개발 연구
  • 천연물로부터 염증조절 및 염증성 질환 억제물질의 탐색과 개발에 관한 연구

최근논문

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미생물학교실 유영춘 교수 최근 대표논문 : 미생물학교실 유영춘 교수 최근 대표논문에 대한 내용입니다.
1. Neuroprotective effects of water extract from brown algae Petalonia binghamiae in an experimental model of focal cerebral ischemia in vitro and in vivo. S.H. Eom, G.L. Hong, H.B. Kang, N.S. Nam, D.K. Kim, Y.G. Jeong, C.S. Kim, Y.C. Yoo, B.H. Lee, J.Y. jung, D.S. Kim, S.Y. Han. CIMB, 45, 8427-8443 (https://doi.org/10.3390/cimb45100531) (2023)
2. Rubus fruticosus leaf extract inhibits vascular dementia-induced memory impairment and neuronal loss by attenuating neuroinflammation. N.S. Sung, S.H. Um, H.B. Kang, N.S. Lee, Y.G. Lee, Y.G. Jeong, D.K. Kim, N.Y. Sung, D.S. Kim, Y.C. Yoo, S.Y. Han. Anatomy & Cell Biol. https://doi.org/10.5115/acb.23.195 (2023)
3. Mixed medicinal mushroom mycelia attenuates Alzheimer’s disease pathologies in vitro and in vivo. J.H. Jeong, G.L. Hong, Y.G. Jeong, N.S. Lee, D.K. Kim, J.Y. Park, M. Park, H.K. Kim, Y.E. Kim, Y.C. Yoo, S.Y. Han. CIMB, 45, 6775-6789 (https://doi.org/10.3390/cimb45080428) (2023)
4. Biological activity of mixed extract of Acanthopanax senticosus and Citrus unshiu fermented with Bivis plumbea for inner beauty. E.J. Kim, S. Y. Kim, S.Y. Kang, Y.C. Yoo, T.J. Yoon, G.W. Lee, Y.H. Cho. J. Life Sci. 33(7), 555-564 (2023)
5. Perilla frutescens leaf extract attenuates vascular dementia-associated memory deficits, neuronal damages, and microglial activation. H.B. Kang, S.H. Kim, S.H. Uhm, D.K. Kim, N.S. lee, Y.G. Jeong, N.Y. Sung, D.S. Kim, I.J. Han, Y.C. Yoo, S.Y. Han. CIMB, 44, 257-272 ( https://doi.org/10.3390/cimb44010019) (2022)
6. Nicotine alleviates alcohol-induced memory and long-term potentiation impairment. J. Jung, S.Y. Choi, T. Xu, E.J, Noh, J.H. Park, S.Y. Han, Y.C. Yoo, K.B. Lee, J.H. Lee, Y.J. Park, D.K. Kim. Neurosci. Lett. https://doi.org/10.1016/j.neulet.2022.136813 (2022)
7. Inhibitory effect of hot-water extract of Gryllus imaculatus (HW-GB) on inflammatory responses and NLRP3 inflammasome activation in macrophages. B. Park, S.Y. Kim, Y.N. Kim, S.D. Kim, Y.C. Yoo. J. Korean Soc. Food Sci. Nutr., 51(2), 115-124 (2022)
8. Bovine lactoferricin induces intestinal epithelial cell activation through phosphorylation of FAK and paxillin and prevents rotavirus infection. Y.Y. Jeong, G.Y. Lee, Y.C. Yoo. J. Mol. Biotech. 31(8), 1175-1182 (2021)
9. NMR-based metabolomics approach to investigate the effects of fruits of Acanthopanax sessiliflorus in a high-fat diet induced mouse model. B.R. Choi, D. Yoon, H.G. Kim, S.M. Oh, Y.C. Yoo, Y.S. Lee, K.W. Kim, T.H. Yi, D.Y. Lee. Metabolites, 11(8), 505 (2021)
10. Water extract of mixed mushroom mycelia grown on a solid barley medium is protective against experimental focal cerebral ischemia. J.H. Jeong, S.H. Kim, M.N. Park, JY Park, C.E. Song, J.H. Moon, A.L. Choi, K.D. Kim, N.S. Lee, Y.G. Jeong, D.K. Kim, B.H. Lee, Y.C. Yoo, S.Y. Han. Curr. Issues Mol. Biol., 43, 365-383 (2021)
11. NMR-Based Metabolomics Approach to Investigate the Effects of Fruits of Acanthopanax sessiliflorus in a High-Fat Diet Induced Mouse Model. Bo-Ram Choi, OrcID,Dahye Yoon, OrcID,Hyoung-Geun Kim, Seon Min Oh, Yung Choon Yoo, Young-Seob Lee, Kwan-Woo Kim, Tae-Hoo Yi, and Dae Young Lee. Metabolites, 11(8), 505, July 2021
12. Bovine Lactoferricin Induces Intestinal Epithelial Cell Activation through Phosphorylation of FAK and Paxillin and Prevents Rotavirus Infection. Ye Young Jeong, Ga Young Lee, and Yung Choon Yoo. J Microbiol Biotechnol, 31(8):1175-1182, August, 2021
13. Water Extract of Mixed Mushroom Mycelia Grown on a Solid Barley Medium Is Protective against Experimental Focal Cerebral Ischemia. Ji Heun Jeong, Shin Hye Kim, Mi Na Park, Jong Yea Park, Hyun Young Park, Chan Eui Song, Ji Hyun Moon, Ah La Choi, Ki Duck Kim, Nam Seob Lee, Young Gil Jeong, Do Kyung Kim, Bong Ho Lee, Yung Choon Yoo, and Seung Yun Han. Curr. Issues Mol. Biol., 43, 365-383, June, 2021
14. Adjuvant Effect of PAMAM Dendrimer on the Antigenicity of Keyhole LimpetHemocyanin in Balb/c Mice. Lee Ga-Young, Kim Min Jee, Kim So Yeon, ,Lee Kyung Bok, Oh Dong Hyun, and Cho Young Ho, Yoo Yung Choon. Journal of Life Science, 30(10):905-911, October, 2020
15. Magnesium Hydride Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia. Myeong Jin Lee, Ji Hye Lee, Do Kyung Kim, Nam Seob Lee, Young Gil Jeong, Ji Heun Jeong, Jong Ho Park, Yung Choon Yoo, and Seung Yun Han. Anatomy & Biological Anthropology, 33(3):125-134, September, 2020
16. Inhibitory effect of the extract of cheonggukjang fermented with Bacillus amyloliquefaciens SCGB 1 on LPS-induced inflammation and inflammatory diseases. So Yeon Kim, Kyung Bok Lee, Young Ho Cho, Do Youn Jeong, Hee Jong Yang, Myeong Seon Ryu, Yung Choon Yoo. Journal of the Korean Society of Food Science and Nutrition, 49(7):659-667 9pages, July. 2020
17. Ginseng Berry Prevents Alcohol-Induced LiverDamage by Improving the Anti-Inflammatory SystemDamage in Mice and Quality Control ofActive Compounds. Dae Young Lee, Min-Jee Kim, Dahye Yoon, Young-Seob Lee, Geum-Soog Kim, Yung Choon Yoo. International Journal of Molecular Science, 20(14):3522, July, 2019
18. Ginsenoside-Rb2 and 20(S)-Ginsenoside-Rg3 from Korean Red Ginseng Prevent Rotavirus Infection in Newborn Mice. Hui Yang, Kwang-Hoon Oh, Hyun Jin Kim, Young Ho Cho, Yung Choon Yoo. Journal of Microbiology and Biotechnology 28(3):391-396, March, 2018
19. Immunomodulating Effect of Extract of Cheonggukjang Fermented with Bacillus amyloliquefaciens(SRCM100730) on RAW 264.7 Macrophages. Seung Bin Choo, Hui Yang, Do-Yuon Jeong, Seong-Yeop Jeong, Myeong Seon Ryu, Kwang-Hoon Oh, Yung Choon Yoo. Journal of the Korean Society of Food Science and Nutrition, 46(11):1300-1307, November, 2017
20. Cloning and analysis of promoter region of mouse immunoglobulin germline γ3 transcripts. Beom-Seok Seo, Hee-Kyung Yoon, JongDae Shin, Ha-Yan Park, Sang-Hoon Lee, Ju-Eon Lee, Yung-Choon Yoo, Junglim Lee, Pyeung-Hyeun Kim & Seok-Rae Park. GENES & GENOMICS, 38, pages1053–1059, July, 2016
21. Dectin-1 agonist selectively induces IgG1 class switching by LPS-activated mouse B cells. Beom-Seok Seo, Ha-Yan Park, Hee-Kyung Yoon, Yung-Choon Yoo, Junglim Lee, and Seok-Rae Park. IMMUNOLOGY LETTERS, October, 2016
22. Phlorofucofuroeckol Improves Glutamate-Induced Neurotoxicity through Modulationof Oxidative Stress-Mediated MitochondrialDysfunction in PC12 Cells. Jwa-Jin Kim, Yoon-Joong Kang, Sun-Ae Shin, Dong-Ho Bak, Jae Won Lee, Kyung Bok Lee, Yung Choon Yoo, Do-Kyung Kim, Bong Ho Lee, Dong Woon Kim, Jina Lee, Eun-Kyeong Jo, and Jae-Min Yuk. PLOS ONE, 11(9):e0163433, September, 2016
23. Anti-Inflammatory Effects of Liriope platyphylla in LPS-Stimulated Macrophages and Endotoxemic Mice. Min-Jee Kim, Yung-Choon Yoo, Nak-Yun Sung, Julim Lee, Seok-Rae Park, Eun-Jung Shon, Bo Dam Lee, and Mee Ree Kim. AMERICAN JOURNAL OF CHINESE MEDICINE, 44(6):1127-1143, September, 2016
24. Antioxidant and Neuroprotective Effects of Green Tea Seed Shell Ethanol Extracts. Nak-Yun Sung, Hayeon Song, Dong-Hyun Ahn, Yung-Choon Yoo, Eui-Baek Byun, Beom-Su Jang, Chulhwan Park, Won-Jong Park, and Eui-Hong Byun. Journal of the Korean Society of Food Science and Nutrition, 45(7), 958～965, July, 2016
25. Comparison Study of Three Varieties of Red Peppers in Terms of Total Total Flavonoid Contents, and Antioxidant Activities. Eui-Baek Byun, Woo-Young Park, Dong-Hyun Ahn, Yung-Choon Yoo, Chulhwan Park, Won-Jong Park, Beom-Su Jang, Eui-Hong Byun, and Nak-Yun Sung. Journal of the Korean Society of Food Science and Nutrition, 45(5):765-770(6 pages), may, 2016
26. Antioxidant and Anti-inflammatory Effects of Extracts from the Flowers of Weigela subsessilis on RAW 264.7 Macrophages. Yung Choon Yoo, Gye Won Lee, and Young Ho Cho. Journal of Life Science, 26(3): 338-345, March, 2016
27. Effects of Fermented Goat Milk on Immunomodulatory Activity and Physical Strength in Mice. Kwang-Hoon Oh, A Rong Kim, Jong-Hwan Bae, Kyung Bok Lee, and Yung Choon Yoo. Journal of the Korean Society of Food Science and Nutrition, 45(2) 174-180(7 pages), February, 2016
28. Induction of Oral Tolerance by Gamma-Irradiated Ovalbumin Administration. Hui Yang, Junglim Lee, Ji Hyun Seo, Kwang Hoon Oh, Young Ho Cho, Yung Choon Yoo. Korean journal for food science of animal resources, 36(1):14-8, February, 2016
29. Cloning and analysis of promoter region of mouse immunoglobulin germline γ3 transcripts. Beom-Seok Seo, Hee-Kyung Yoon, JongDae Shin, Ha-Yan Park, Sang-Hoon Lee, Ju-Eon Lee, Yung-Choon Yoo, Junglim Lee, Pyeung-Hyeun Kim & Seok-Rae Park. GENES & GENOMICS, 38:1053–1059, July, 2016

이정림 교수 (Lee, Jung lim)

연구분야

  • 이식면역관용 기전에 관한 연구
  • 면역관용에서 조절 T 림프구의 역할에 대한 연구
  • 수지상세포의 면역 조절 기능에 대한 연구
  • 생체 기능성 물질의 면역활성에 대한 연구

최근논문

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미생물학교실 이정림 교수 최근 대표논문 : 미생물학교실 이정림 교수 최근 대표논문에 대한 내용입니다.
1. Cloning and analysis of promoter region of mouse immunoglobulin germline γ3 transcripts. Beom-Seok Seo, Hee-Kyung Yoon, JongDae Shin, Ha-Yan Park, Sang-Hoon Lee, Ju-Eon Lee, Yung-Choon Yoo, Junglim Lee, Pyeung-Hyeun Kim & Seok-Rae Park. GENES & GENOMICS, 38:1053–1059, July, 2016
2. Dectin-1 agonist selectively induces IgG1 class switching by LPS-activated mouse B cells. Beom-Seok Seo, Ha-Yan Park, Hee-Kyung Yoon, Yung-Choon Yoo, Junglim Lee, and Seok-Rae Park. IMMUNOLOGY LETTERS, 178:114-121, October, 2016
3. Induction of Oral Tolerance by Gamma-Irradiated Ovalbumin Administration. Hui Yang, Junglim Lee, Ji Hyun Seo, Kwang Hoon Oh, Young Ho Cho, Yung Choon Yoo. Korean journal for food science of animal resources, 36(1):14-8, February, 2016
4. Anti-Inflammatory Effects of Liriope platyphylla in LPS-Stimulated Macrophages and Endotoxemic Mice. Min-Jee Kim, Yung-Choon Yoo, Nak-Yun Sung, Julim Lee, Seok-Rae Park, Eun-Jung Shon, Bo Dam Lee, and Mee Ree Kim. The American Journal of Chinese Medicine, 44(6):1127-1143, September, 2016

박석래 교수 (Park, Seok-Rae)

연구분야

  • B세포에 의한 항체생산 기전(Ig class switching 중심) 및 B세포 발달/분화에 대한 연구
  • B세포의 항원제시세포(APC, antigen-presenting cell) 기능에 대한 연구
  • 배아 착상능력 및 자궁내막 수용성(endometrial receptivity) 향상에 대한 연구

최근논문

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미생물학교실 박석래 교수 최근 대표논문 : 미생물학교실 박석래 교수 최근 대표논문에 대한 내용입니다.
1. Exosomal miR-205-5p Improves Endometrial Receptivity by Upregulating E-cadherin Expression through ZEB1 Inhibition. International Journal of Molecular Sciences, 24(20):15149, 2023.
2. Efficacy of Low-Level Laser Therapy in a Rabbit Model of Rhinosinusitis, International Journal of Molecular Sciences, 24(1):760, 2023.
3. Lactoferrin-derived chimeric peptide (LFch) strongly boosts TGFβ1-mediated inducible Treg differentiation possibly through downregulating TCR/CD28 signalling. Immunology, 168(1):110-119, 2023.
4. Impairment of Decidualization of Endometrial Stromal Cells by hsa-miR-375 Through NOX4 Targeting. Reproductive Sciences, 29(11):3212-3221, 2022.
5. The miR-182-5p/NDRG1 Axis Controls Endometrial Receptivity through the NF-κB/ZEB1/E-Cadherin Pathway. International Journal of Molecular Sciences, 23(20):12303, 2022.
6. SIRT1 suppresses in vitro decidualization of human endometrial stromal cells through the downregulation of forkhead box O1 expression. Reproductive Biology, 22(3):100672, 2022.
7. Tobacco Smoking Could Accentuate Epithelial-Mesenchymal Transition and Th2-Type Response in Patients With Chronic Rhinosinusitis With Nasal Polyps. Immune Network, 22(4):e35, 2022.
8. Lactoferrin Potentiates Inducible Regulatory T Cell Differentiation through TGF-β Receptor III Binding and Activation of Membrane-Bound TGF-β. Journal of Immunology, 207(10):2456-2464, 2021.
9. Transcriptomic analysis and competing endogenous RNA network in the human endometrium between proliferative and mid-secretory phases. Experimental and Therapeutic Medicine, 21(6):660, 2021.
10. Sestrin2 Mediates IL-4-induced IgE Class Switching by Enhancing Germline ε Transcription in B Cells. Immune Network, 20(2):e19, 2020.
11. SIRT1 Alleviates LPS-Induced IL-1β Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts. Cells, 9(3):728, 2020.
12. Decursinol from Angelica gigas Nakai enhances endometrial receptivity during implantation. BMC Complementary Medicine and Therapies, 20(1):36, 2020.
13. The Nod2 Agonist Muramyl Dipeptide Cooperates with the TLR4 Agonist Lipopolysaccharide to Enhance IgG2b Production inMouse B Cells. Journal of Immunology Research, 2019:2724078, 2019.
14. Increase of Hspa1a and Hspa1b genes in the resting B cells of Sirt1 knockout mice. Molecular Biology Reports, 46(4):4225-4234, 2019.
15. The TLR7 agonist imiquimod selectively inhibits IL-4-induced IgE production by suppressing IgG1/IgE class switching and germline ε transcription through the induction of BCL6 expression in B cells. Cellular Immunology, 338:1-8, 2019.
16. Heat-Killed Saccharomyces cerevisiae, A Dectin-1 Agonist, Selectively Induces IgG4 Production by Human B Cells. Immune Network, 18(6):e46, 2018.
17. Toll-like Receptor 1/2 Agonist Pam3CSK4 Suppresses Lipopolysaccharide-driven IgG1 Production while Enhancing IgG2a Production by B Cells. Immune Network, 18(1):e10, 2018.
18. Mechanism underlying the suppressor activity of retinoic acid on IL4-induced IgE synthesis and its physiological implication. Cellular Immunology, 322:49-55, 2017.
19. Expression of activation-induced cytidine deaminase splicing variants in patients with ankylosing spondylitis. Autoimmunity, 50(8):435-440, 2017.
20. Aberrant expression of interleukin-10 and activation-induced cytidine deaminase in B cells from patients with Behcet's disease. Biomedical Reports, 7(6):520-526, 2017.
21. Cloning and analysis of promoter region of mouse immunoglobulin germline γ3 transcripts. Genes & Genomics, 38:1053-1059, 2016.
22. Dectin-1 agonist selectively induces IgG1 class switching by LPS-activated mouse B cells. Immunology Letters, 178:114-121, 2016.