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페이스북 트위터 print

양승주
양승주
(Yang, seung-ju)
  • 직급 교수
  • 소속명 임상병리학과
  • 연구실 메디컬캠퍼스 보건학관 307호
  • 전화 042-600-8432
  • e메일 sjyang@konyang.ac.kr
  • 학위명 이학박사

논문

  • MiR-30a-5p and miR-153-3p regulate LPS-inducedneuroinflammatory response and neuronal apoptosis bytargeting NeuroD1 BMB Reports 2022.09.30
  • miR-30a-5p Augments the Anti-inflammatory Effects of Dexmedetomidine in LPS-induced BV2 Cells Korean Journal of Clinical Laboratory Science 2022.09.30
  • Anti-inflammatory effects of N-cyclooctyl-5-methylthiazol-2-aminehydrobromide on lipopolysaccharide-induced inflammatory response through attenuation of NLRP3 activation in microglial cells BMB reports 2021.11.30
  • Hypoxia-Induced S100A8 Expression Activates MicroglialInflammation and Promotes Neuronal Apoptosis International Journal of Molecular Sciences 2021.01.26
  • Noni Inhibits Neuronal Damage Caused by the Immune Reaction of Microglial Cells Activated by Doxorubicin 대한임상검사과학회지 2020.12.30
  • N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons BMB Reports 2020.10.31
  • Metformin or α-Lipoic Acid Attenuate Inflammatory Response and NLRP3 Inflammasome in BV-2 Microglial Cells 대한임상검사과학회지 2020.09.30
  • S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells Frontiers in immunology 2020.08.06
  • Effects of a-lipoic acid on LPS-induced neuroinflammation andNLRP3 inflammasome activation through the regulation ofBV-2 microglial cells activation BMB Reports 2019.10.31
  • KHG21834 attenuates glutamate-induced mitochondrial damage, apoptosis,and NLRP3 inflammasome activation in SH-SY5Y human neuroblastomacells European Journal of Pharmacology 2019.05.24
  • Anti-inflammatory Effects of Metformin on Neuro-inflammation and NLRP3 Inflammasome Activation in BV-2 Microglial Cells 대한의생명과학회지 2019.03.31
  • 3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP+-induced cytotoxicity by regulating oxidative stress and mitochondrial dysfunction in SH-SY5Y cells BMB REPORTS 2018.11.30
  • 3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates NLRP3 inflammasome-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglial cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2018.01.01
  • Anti-inflammatory and anti-oxidative effects of 3-(naphthalen-2-yl(propoxy) methyl) azetidine hydrochloride on beta-amyloid-induced microglial activation BMB REPORTS 2017.12.31
  • N-Adamantyl-4-Methylthiazol-2-Amine Attenuates Glutamate-Induced Oxidative Stress and Inflammation in the Brain Neurotoxicity Research 2017.07.01
  • Protective effect of 3-(naphthalen-2-yl(propocy)methyl)azetidine hydrochloride on hypoxia-induced toxicity by suppressing microglial activation in BV-2 cells BMB REPORTS 2016.12.31
  • S100A8 Induces Secretion of MCP-1, IL-6, and IL-8 via TLR4 in Jurkat T Cells 대한의생명과학회지 2016.06.29
  • N-Adamantyl-4-methylthiazol-2-amine suppresses amyloid beta-induced neuronal oxidative damage in cortical neurons FREE RADICAL RESEARCH 2016.04.11
  • 정신분열증 치료제에 의한사람 글루탐산염 탈수소효소 동종효소의 억제효과 한국산학기술학회논문지 2016.01.31
  • The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microglia NEUROTOXICOLOGY 2015.10.30
  • 2-Cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride alters lipopolysaccharide-induced proinflammatory cytokines and neuronal morphology in mouse fetal brain NEUROPHARMACOLOGY 2015.10.29
  • O6-Methylguanine-DNA methyltransferase (MGMT) gene expression is associated with ultraviolet B (UVB)-induced cell growth inhibition and recovery GENES & GENOMICS 2015.09.01
  • The ABCG2 Polymorphism rs2725220 Is Associated with Hyperuricemia in the Korean Population Genomics & Informatics 2014.12.01
  • Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats EUROPEAN JOURNAL OF PHARMACOLOGY 2014.08.01
  • Inhibition of glutamate dehydrogenase and insulin secretion by KHG26377 does not involve ADP-ribosylation by SIRT4 or deacetylation by SIRT3 BMB reports 2012.08.31
  • Increased expression of interleukin-1b in triglyceride-induced macrophage cell death is mediated by p38 MAP kinase BMB Reports 2012.05.09
  • 흡연이 치은열구액 내 Matrix Metalloproteinase-9에 미치는 영향 치위생과학회지 2011.08.01
  • Comperative analysis of screening results from various ELISA formats used for detection of anti-erythropoietin antibodies in korean patients Biomolecules & Therapeutics 2010.04.30
  • Inhibitory effects of KHG26377 on glutamate dehydrogenase activity in cultured islets BMB reports 2010.04.30
  • Immunogenicity of recombinant human erythropoietin:clinical cases, causes and assays Journal of Experimental Biomedical Science 2009.06.30
  • Isoliquiritigenin의 toll-like receptor agonists에 의해서 유도된 NF-kB활성화와 cyclooxygenase-2 발현 억제 한국식품과학회지 2009.05.01
  • Small-interfering-RNA-mediated silencing of human glutamate dehydrogenase induces apoptosis in neuroblastoma cells Biotechnology and applied biochemistry 2008.09.18
  • Serine/Arginine Protein-Specific Kinase 2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1 Cancer Research 2008.06.15
  • Soluble expression and purification of synthetic human bone morphogenetic protein-2 in Escherichia coli BMB reports 2008.05.31
  • Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatic condensation Cell Death and Differentiation 2007.12.14
  • Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquine Journal of Biochemistry and Molecular Biology 2007.11.01
  • Akt phosphorylates Mst1 and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation Journal of Biological Chemistry 2007.10.19
  • Alteration of the quaternary structure of human UDP-glucose dehydrogenase by a double mutation Journal of Biochemistry and Molecular Biology 2007.09.05
  • Protective effect of benzothiazole derivative KHG21834 on amyloid b-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons TOXICOLOGY 2007.07.17
  • Amino Acid Change within Antenna Helix Are Responsible for Different Regulatory Preferences of Human Glutamate Dehydrogenase Isozymes The Journal of Biological Chemistry 2007.07.06

저서

  • 임상화학 I, II 수문사 2021.03.09
  • 임상분자진단학 PACIFIC BOOKS 2009.09.10
  • 현대 임상병리학의 이해 정문각 2008.11.20

연구과제

  • 한국연구재단 저산소증으로 인한 염증이 신경세포 직접교차분화에 미치는 영향과 S100A8/A9에 의한 NeuroD1 억제 메커니즘 규명 2023.03.01 ~ 2024.02.29
  • 한국연구재단 저산소증으로 인한 염증이 신경세포 직접교차분화에 미치는 영향과 S100A8/A9에 의한 NeuroD1 억제 메커니즘 규명 2022.03.01 ~ 2023.02.28
  • 건양대학교 Anti-inflammatory efects of N-cyclooctyl-5-methylthiazol-2-amine hydrobromide on lipopolysacharide-induced inflammatory response through atenuation of NLRP3 activation in microglial cels 2021.09.01 ~ 12.31
  • 한국연구재단 저산소증으로 인한 염증이 신경세포 직접교차분화에 미치는 영향과 S100A8/A9에 의한 NeuroD1 억제 메커니즘 규명 2021.06.01 ~ 2022.02.28
  • 건양대학교 덱스메데토미딘의 신경염증 억제효과에 대한 마이크로RNA 30a의 영향 2021.05.01 ~ 2022.04.30
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 기능 규명 2021.03.01 ~ 05.31
  • 건양대학교 Hypoxia-induced S100A8 expression activates microglial inflammation and promotes neuronal apoptosis 2020.11.01 ~ 2021.02.28
  • 건양대학교 임상화학 I, II 2020.08.01 ~ 2021.02.26
  • 건양대학교 N-Adamanty1-4-methylthiazo1-2-amine suppresses glutamate-induced autophagic cell death PI3K/Akt/mTOR signaling pathways in cortical neurons 2020.07.01 ~ 10.15
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 기능 규명 2020.03.01 ~ 2021.02.28
  • 건양대학교 Metformin or α-Lipoic Acid Attenuate Inflammatory Response and NLRP3 Inflammasome in BV-2 Microglial Cells 2020.03.01 ~ 09.18
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 기능 규명 2019.03.01 ~ 2020.02.29
  • 한국과학창의재단 신경염증반응을 통함 허혈성 뇌질환에서 자기소화작용과 손상연관분자패턴의 관계에 관한 연구 2018.07.01 ~ 12.31
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 기능 규명 2018.06.01 ~ 2019.02.28
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 규명 2017.06.01 ~ 2018.05.31
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 규명 2016.06.01 ~ 2017.05.31
  • 한국과학창의재단 베타아밀로이드 단백질에 의한 허혈성 뇌질환에 미치는 아세틸엘카르니틴과 리포산의 효과에 관한 연구 2016.06.01 ~ 11.30
  • 한국연구재단 신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 기능 규명 2015.06.01 ~ 2016.05.31
  • 글루탐산 조절에 의한 정신분열증 작용기전 규명을 위한 분자생화학적 연구 2011.05.01 ~ 2012.04.30
  • 한국과학재단 신경 특이성 글루탐산 분해효소와 관련된 정신분열증 작용기전 규명을 위한 분자생화학적 연구 2009.05.01 ~ 2010.04.30

대외활동

  • 2020.08.14 ~ 2022.08.13 한국임상병리학과 임상화학교수회 회장 회장
  • 2016.03.12 ~ 2018.03.11 대전광역시 서구 건강도시운영위원회 위원 서구 건강도시운영위원회 위원
  • 2016.01.01 ~ 2017.12.31 대한의생명과학회지 편집 및 심사 편집간사(상임이사)
  • 2014.03.12 ~ 2016.03.11 대전광역시 서구 건강도시 운영위원회 위원 건강도시 운영위원
  • 2012.01.01 ~ 2013.12.31 대한의생명과학회지 편집 및 심사 편집간사 (상임이사)
  • 2010.01.01 ~ 2011.12.31 대한의생명과학회 총무간사 총무간사(상임이사)