MiR-30a-5p and miR-153-3p regulate LPS-inducedneuroinflammatory response and neuronal apoptosis bytargeting NeuroD1BMB Reports2022.09.30
miR-30a-5p Augments the Anti-inflammatory Effects of Dexmedetomidine in LPS-induced BV2 CellsKorean Journal of Clinical Laboratory Science2022.09.30
Anti-inflammatory effects of N-cyclooctyl-5-methylthiazol-2-aminehydrobromide on lipopolysaccharide-induced inflammatory response through attenuation of NLRP3 activation in microglial cellsBMB reports2021.11.30
Hypoxia-Induced S100A8 Expression Activates MicroglialInflammation and Promotes Neuronal ApoptosisInternational Journal of Molecular Sciences2021.01.26
Noni Inhibits Neuronal Damage Caused by the Immune Reaction of Microglial Cells Activated by Doxorubicin대한임상검사과학회지2020.12.30
N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neuronsBMB Reports2020.10.31
Metformin or α-Lipoic Acid Attenuate Inflammatory Response and NLRP3 Inflammasome in BV-2 Microglial Cells대한임상검사과학회지2020.09.30
S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia CellsFrontiers in immunology2020.08.06
Effects of a-lipoic acid on LPS-induced neuroinflammation andNLRP3 inflammasome activation through the regulation ofBV-2 microglial cells activationBMB Reports2019.10.31
KHG21834 attenuates glutamate-induced mitochondrial damage, apoptosis,and NLRP3 inflammasome activation in SH-SY5Y human neuroblastomacellsEuropean Journal of Pharmacology2019.05.24
Anti-inflammatory Effects of Metformin on Neuro-inflammation and NLRP3 Inflammasome Activation in BV-2 Microglial Cells대한의생명과학회지2019.03.31
3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP+-induced cytotoxicity by regulating oxidative stress and mitochondrial dysfunction in SH-SY5Y cellsBMB REPORTS2018.11.30
3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates NLRP3 inflammasome-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglial cellsBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS2018.01.01
Anti-inflammatory and anti-oxidative effects of 3-(naphthalen-2-yl(propoxy) methyl) azetidine hydrochloride on beta-amyloid-induced microglial activationBMB REPORTS2017.12.31
N-Adamantyl-4-Methylthiazol-2-Amine Attenuates Glutamate-Induced Oxidative Stress and Inflammation in the BrainNeurotoxicity Research2017.07.01
Protective effect of 3-(naphthalen-2-yl(propocy)methyl)azetidine hydrochloride on hypoxia-induced toxicity by suppressing microglial activation in BV-2 cellsBMB REPORTS2016.12.31
S100A8 Induces Secretion of MCP-1, IL-6, and IL-8 via TLR4 in Jurkat T Cells대한의생명과학회지2016.06.29
The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microgliaNEUROTOXICOLOGY2015.10.30
2-Cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride alters lipopolysaccharide-induced proinflammatory cytokines and neuronal morphology in mouse fetal brainNEUROPHARMACOLOGY2015.10.29
O6-Methylguanine-DNA methyltransferase (MGMT) gene expression is associated with ultraviolet B (UVB)-induced cell growth inhibition and recoveryGENES & GENOMICS2015.09.01
The ABCG2 Polymorphism rs2725220 Is Associated with Hyperuricemia in the Korean PopulationGenomics & Informatics2014.12.01
Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic ratsEUROPEAN JOURNAL OF PHARMACOLOGY2014.08.01
Inhibition of glutamate dehydrogenase and insulin secretion by KHG26377 does not involve ADP-ribosylation by SIRT4 or deacetylation by SIRT3BMB reports2012.08.31
Increased expression of interleukin-1b in triglyceride-induced macrophage cell death is mediated by p38 MAP kinaseBMB Reports2012.05.09
흡연이 치은열구액 내 Matrix Metalloproteinase-9에 미치는 영향치위생과학회지2011.08.01
Comperative analysis of screening results from various ELISA formats used for detection of anti-erythropoietin antibodies in korean patientsBiomolecules & Therapeutics2010.04.30
Inhibitory effects of KHG26377 on glutamate dehydrogenase activity in cultured isletsBMB reports2010.04.30
Immunogenicity of recombinant human erythropoietin:clinical cases, causes and assaysJournal of Experimental Biomedical Science2009.06.30
Isoliquiritigenin의 toll-like receptor agonists에 의해서 유도된 NF-kB활성화와 cyclooxygenase-2 발현 억제한국식품과학회지2009.05.01
Small-interfering-RNA-mediated silencing of human glutamate dehydrogenase induces apoptosis in neuroblastoma cellsBiotechnology and applied biochemistry2008.09.18
Serine/Arginine Protein-Specific Kinase 2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1Cancer Research2008.06.15
Soluble expression and purification of synthetic human bone morphogenetic protein-2 in Escherichia coliBMB reports2008.05.31
Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatic condensationCell Death and Differentiation2007.12.14
Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquineJournal of Biochemistry and Molecular Biology2007.11.01
Akt phosphorylates Mst1 and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocationJournal of Biological Chemistry2007.10.19
Alteration of the quaternary structure of human UDP-glucose dehydrogenase by a double mutationJournal of Biochemistry and Molecular Biology2007.09.05
Protective effect of benzothiazole derivative KHG21834 on amyloid b-induced neurotoxicity in PC12 cells and cortical and mesencephalic neuronsTOXICOLOGY2007.07.17
Amino Acid Change within Antenna Helix Are Responsible for Different Regulatory Preferences of Human Glutamate Dehydrogenase IsozymesThe Journal of Biological Chemistry2007.07.06
저서
임상화학 I, II수문사2021.03.09
임상분자진단학PACIFIC BOOKS2009.09.10
현대 임상병리학의 이해정문각2008.11.20
연구과제
한국연구재단저산소증으로 인한 염증이 신경세포 직접교차분화에 미치는 영향과 S100A8/A9에 의한 NeuroD1 억제 메커니즘 규명2023.03.01 ~ 2024.02.29
한국연구재단저산소증으로 인한 염증이 신경세포 직접교차분화에 미치는 영향과 S100A8/A9에 의한 NeuroD1 억제 메커니즘 규명2022.03.01 ~ 2023.02.28
건양대학교Anti-inflammatory efects of N-cyclooctyl-5-methylthiazol-2-amine hydrobromide on lipopolysacharide-induced inflammatory response through atenuation of NLRP3 activation in microglial cels2021.09.01 ~ 12.31
한국연구재단저산소증으로 인한 염증이 신경세포 직접교차분화에 미치는 영향과 S100A8/A9에 의한 NeuroD1 억제 메커니즘 규명2021.06.01 ~ 2022.02.28
건양대학교덱스메데토미딘의 신경염증 억제효과에 대한 마이크로RNA 30a의 영향2021.05.01 ~ 2022.04.30
한국연구재단신경염증 반응을 통한 허혈성 뇌질환에 미치는 베타아밀로이드 단백질의 기능 규명2021.03.01 ~ 05.31